Abstracts/Proceedings

2004

1. Hlastala MP, Schimmel C, Anderson JC, Bernard S, and Lakshminarayan S. Exchange of highly soluble gases in the lung airways with the bronchial circulation. Eur. Resp. J. 24(Suppl 48): 327s, 2004.
2. Corley RA. (2004). Incorporation of medical imaging and supercomputing in the development and validation of biologically based exposure-dose-response models: An example from the respiratory system. 7th International Neuroprotective Conference and Workshop on PBPK/PD Models for Developing Humans: Risk Assessment Strategies and Research Recommendations. Pacific Grove, CA. November 14-19, 2004. (Invited)

2005

1. Anderson JC and Hlastala MP. Impact of airway gas exchange on the multiple inert gas elimination technique. Amer J Resp Crit Care Med 168: A581, 2005.
2. Anderson JC, Lamm WJE and Hlastala MP. Measuring endogenous acetone during a single exhalation breathing maneuver. BMES annual meeting. Baltimore, MD, Sept 28-Oct 1, 2005.
3. Corley RA. (2005). Development and validation of 4-dimensional models of the respiratory system. National Academy of Sciences, Workshop of the Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents. Washington, D.C. July 6-7, 2005. (Invited)
4. Corley RA, Einstein DR, Hoffman EA, Jacob RE, Minard KR, Postlethwait EM, Timchalk C, Trease LL, and Trease HE. (2005). Development of computational fluid dynamics models of the respiratory system for gas, vapor and particulate dosimetry. Symposium on Applied Modeling and Computations in Nuclear Science, 230th American Chemical Society National Meeting. Washington, D.C. Abst. #NUCL-18. August 28-September 1, 2005. (Invited)
5. Corley RA, Minard KR, Trease HE, Trease LL, Timchalk C, Plopper CG, Harkema JR, Kimbell JS, and Postlethwait EM. (2005). Rapid 3D mesh construction and respiratory airflow modeling in laboratory animals. Abst. #3170. 100th Anniversary International Conference, American Thoracic Society. San Diego, CA. May 20-25, 2005.
6. Jacob RE, Minard KR, Einstein DR, Corley RA, Trease HE, Trease LL, and Saam B. (2005). Validation of CFD airflow simulations using 3He Magnetic Resonance Imaging. Abst. #3956. 100th Anniversary International Conference, American Thoracic Society. San Diego, CA. May 20-25, 2005.
7. Jacob RE, Minard KR, Wiseman D, Saam B. (2005). Production of highly polarized 3He for magnetic resonance imaging, Abstract no. C1.00010. Northwest Section of the American Physical Society, Victoria, BC, Canada, May 13-14, 2005.
8. Minard KR, Corley RA, Timchalk C, and Robertson HT. (2005). 3He Magnetic resonance imaging of particulate matter dosimetry. Abst. #3177. 100th Anniversary International Conference, American Thoracic Society. San Diego, CA. May 20-25, 2005.
9. Timchalk C, Minard KR, Jacob RE, Trease HE, Einstein DR, Trease LL, Kabilan S, and Corley RA. Magnetic resonance imaging and computational fluid dynamic (CFD) modeling of the rat respiratory system: Mesh development, airflow dynamics and particulate matter deposition. Frontiers in Aerosol Dosimetry Research Conference. Irvine, CA. October 24-25, 2005.
10. Trease H, Trease L, Corley R, Fowler J, and Einstein D. (2005). Building geometry and meshes for simulating the respiratory system of mammals. 8th U.S. National Congress on Computational Modeling. Austin, TX. July 25-27, 2005.
11. Trease L, Trease H, Corley R, Fowler J, and Einstein D. (2005). Building geometry and meshes for simulating the respiratory system of mammals. 9th International Conference on Numerical Grid Generation. San Jose, CA. June 11-18, 2005.

2006

1. Anger BC, Jacob RE, Minard KR, and Saam B. (2006). Rapid production of hyperpolarized 3He gas for MRI. ISMRM 14th Scientific Meeting, Seattle, WA, May 6-12, 2006.
2. Bassingthwaighte JB. Balances in Cellular metabolism and energetics: Principles in modeling. Mathematical Modeling in Nutrition and the Health Sciences Proc: 15, 2006.
3. Bassingthwaighte J. Capillarity, regional blood flows, and metabolism. Proc Eur Conf Microcirc SNE1, 2006.
4. Bassingthwaighte JB, Matuszkiewicz A, Krueger M, Park JS, Raymond GM, Butterworth E, Neal M, and Hlastala M. The physiome in pharmacokinetics, pharmacodynamics and toxicology. Workshop: "Towards the virtual human: Adding more physiological detail to biologically based models used in risk assessments". Abst. #34. 45th Annual Meeting of the Society of Toxicology. San Diego, CA. March 5-9, 2006.
5. Bassingthwaighte JB, Neal ML, Dash RK, Carlson BE, and Anderson JC. (2006). The Role of Hemoglobin in Respiratory Gas Exchanges. 34th Conf Int. Soc. Oxygen Transport to Tissue 34: 41.
6. Carlson BE, Anderson JC, Raymond GR, Dash RK, and Bassingthwaighte JB. (2006). Modeling oxygen and carbon dioxide transport and exchange in a closed-circulatory system. Adv. Exp. Med. and Biol.: Int Soc Oxygen Transport to Tissue.
7. Corley RA, Minard KR, Einstein DR, Jacob RE, Kabilan S, Trease LL, Hoffman EA, Postlethwait E, Plopper C, Kimbell JS, Harkema J, Hlastala M and Timchalk C. Advancements in modeling the respiratory system. Workshop: "Towards the virtual human: Adding more physiological detail to biologically based models used in risk assessments". Abst. #35. 45th Annual Meeting of the Society of Toxicology. San Diego, CA. March 5-9, 2006. (Invited)
8. Corley RA, Minard KR, Jacob RE, Einstein DR, Kuprat AP, Kabilan S, Timchalk C, Trease LL, Fowler J, Asgharian B, Wong BA, and Kimbell JS. New technologies for developing and confirming computational fluid dynamics models of respiratory drug delivery. 2006 American Association of Pharmaceutical Scientists Annual Meeting and Exposition. October 29 – November 2, 2006. San Antonio, TX.
9. Corley RA, Minard KR, Jacob RE, Einstein DR, Kuprat AP, Kabilan S, Trease LL, Teeguarden JG, Robertson HT, Asgharian B, and Timchalk C. Particokinetics and the development of virtual respiratory system models. Nanotechnology 2006: Toxicology of Nanoparticles. American Association for the Advancement of Science Annual Meeting. St. Louis, MO. February 17, 2006. (Invited)
10. Kimbell JS. Using computer-assisted airway reconstruction to define dose-response relationships. Continuing Education course "Assessing Airway Injury and Remodeling Induced by Inhaled Pollutants using Magnetic Resonance Imaging, Microscopy, and Modeling". 45th Annual Meeting of the Society of Toxicology. San Diego, CA. March 5-9, 2006. (Invited)
11. Laicher G and Saam B. Spin-lattice relaxation and diffusion of hyperpolarized helium in phantoms. 14th An. International Society for Magnetic Resonance in Medicine. Seattle, WA, May 6-12, 2006.
12. Minard KR and Jacob RE. Quantitative MR imaging of 3He gas transport in model airways. 14th An. International Society for Magnetic Resonance in Medicine. Seattle, WA, May 6-12, 2006.
13. Plopper CG. State-of-the-art techniques for imaging the upper and lower respiratory tract: Identifying macroscopic to microscopic airway alterations caused by airborne toxicants. Continuing Education course "Assessing Airway Injury and Remodeling Induced by Inhaled Pollutants using Magnetic Resonance Imaging, Microscopy, and Modeling". 45th Annual Meeting of the Society of Toxicology. San Diego, CA. March 5-9, 2006. (Invited)
14. Rubin DR, Grossman D, Neal ML, Cook DL, Bassingthwaighte JB, and Musen M. Ontology-based representation of simulation models of physiology. Amer Med Informatics Assoc 2006 Symposium Proc 664-668, 2006.

2007

1. Anger, B., Jacob, R.E. Minard, K.R. and Saam. B. Rapid Production of Hyperpolarized 3He Gas for MRI. American Physical Society, Denver, CO, March 5-9, 2007.
2. Bassingthwaighte JB, Raymond GM, Carlson BE, Hawley S, Qian H, Atlas L, and Chizeck H. Multiscale adaptive modeling of the cardiovascular system. Multiscale Modeling (MSM) Consortium , 2007.
3. Carey SA, Garcia GJM, Minard KR, Einstein DR, Ballinger CA, Wagner JG, Plopper CG, Corley RA, Postlethwait EM, Kimbell JS, and Harkema JR. Use of magnetic resonance (MR) imaging, light microscopy and three-dimensional (3D) reconstruction in epithelial mapping of the nasal airways of infant Rhesus monkeys. International Conference of the American Thoracic Society. San Francisco, CA. May 18-23, 2007.
4. Corley RA. A virtual model of the lung for the study of environment-disease interactions. U.S. EPA International Science Forum on Computational Toxicology. RTP, NC. May 21-23, 2007.
5. Einstein DR, Richmond MC, Perkins WA, Kuprat AP, Minard KR, Jacob RE, Timchalk C, and Corley RA. Particle deposition in an imaging based geometry of the Sprague-Dawley rat. 46th Annual Meeting of the Society of Toxicology. Charlotte, NC. March 25-29, 2007.
6. Hawley S, Atlas L, and Chizeck H. Empirical mode decomposition: Development of a method for recognition of abnormalities in multiscale model solutions. Multiscale Modeling (MSM) Consortium , 2007.
7. Jacob RE and Minard KR. Quantitative magnetic resonance imaging of 3He gas transport. American Physical Society. Denver, CO, March 5-9, 2007.
8. Kuprat AP, Einstein DR, Minard KR, Jacob RE, Timchalk C, and Corley RA. Computational fluid dynamics predictions of hyperpolarized helium flows. 46th Annual Meeting of the Society of Toxicology. Charlotte, NC. March 25-29, 2007.
9. Nazridoust K and Asgharian B. Prediction of airflow and particle deposition in the human lung. 46th Annual Meeting of the Society of Toxicology. Charlotte, NC. March 25-29, 2007.
10. Raymond GM, Bassingthwaighte JB, and Butterworth E. Mathematical modeling of organ systems, tissues or cells:. FASEB J (Online version) 000, 2007.
11. Robertson HT, Bernard SL, Lamm WJE, Glenny RW. Images of inhaled 1.0-µm and 0.04-µm aerosolized fluorescent microspheres (FMS) in the rat reveal an acinar pattern of deposition reflecting regional ventilation (rVA). International Conference of the American Thoracic Society. San Francisco, CA. May 18-23, 2007.
12. Wong BA, Tewksbury EW, Garcia GJM, and Kimbell JS. Deposition efficiency of inhaled particles from 30 nm to 10 µm in different human nasal replicas. 46th Annual Meeting of the Society of Toxicology. Charlotte, NC. March 25-29, 2007.

2008

1. Jacob, R.E., Gideon, K.M., Minard, K.R., and Timchalk C. In Vivo Evaluation of Lung Structure by Magnetic Resonance Imaging (MRI) Following Elastase Induced Emphesema in Rats. 47th Annual Meeting of the Society of Toxicology. Seattle, WA. March 16-20, 2008.
2. Jacob, R.E. and Minard, K.R. Physics and the Lungs. 10th Annual Meeting of the Northwest Section of the American Physical Society. Portland, OR. May 15-17, 2008.
3. Dyedov V, Einstein DR, Jiao X, Kuprat AP, and del Pin F. Scale-invariant boundary-layer mesh generation using face offsetting for biomedical computing. 17th International Meshing Roundtable, Pittsburgh, PA. October 12-15, 2008. (Best Student Poster Award Winner).

2009

1. Corley RA, Minard KR, Jacob RE, Timchalk C, Kuprat AP, Carson JP, Kabilan S, Frevert C, Fanucchi M, and Einstein DR. Virtual organ models for multi-scale integration of dose-response relationships. 48th Annual Meeting of the Society of Toxicology. Baltimore, MD. March 15-19, 2009. (Invited).

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